Iyo Alpha Lipoic Acid Yakaderera Ropa Kuwedzera?

Hypertension kana hypertension chinhu chakakosha chekubhejera chirwere checoronary, sitiroko, uye mamwe matambudziko emoyo. Nekuwedzera kwematanho ehypertension kutenderera pasirese, kufarira kwakakura kutenderedza kurapa kwakakosha senge Arifa lipoic asidhi (ALA) kubatsira kutenderera kuomarara kudzora. ALA ndeye endogenous antioxidant ine huwandu hwezvinonzi mabhenefiti. Asi kuwedzera neALA kunogona kubatsira zvechokwadi kugadzirisa BP? Kuongorora humbowo hwesainzi hwazvino hunogona kupa humbowo mune zvinogona antihypertensive mhedzisiro yeALA uye kutungamira kwayo kwakachengeteka, kushandiswa kwakakodzera.

 

Chii chinonzi Alpha-Lipoic Acid Inobatsira?

 

Alpha-lipoic acid chinhu chinowanzo kuitika chinogadzirwa zvine mwero mumuviri. Iyo inozadza se cofactor yemapuroteni anobata simba rekugaya uye kugona seyo yakasimba sero reinforcement. ALA inowanikwawo mune dzakasiyana siyana zvekudya sespinachi, broccoli, mbatatisi, itsvo bhinzi, uye nyama. Nekudaro, zvekuwedzera zvinopa sosi yakamisikidzwa mumadosi asingawanikwe nyore kuburikidza nekudya chete.

 

Kumwe kushandiswa kwakakosha kweALA supplements kunosanganisira:

-Antioxidant dziviriro kubva kune oxidative kusagadzikana uye mahara radicals.

-Kutsigira hutano hwehuga hweropa uye peripheral nerve function.

- Inogona kubatsira kuderedza uremu kana yasanganiswa neL-carnitine.

- Zvinogona kunonoka kuderera kwekuziva uye neurodegenerative chirwere kufambira mberi.

-Kuderedza matambudziko ane chekuita nechirwere cheshuga sekukuvara kwetsinga uye matambudziko eziso.

Nekuita kwayo kwe antioxidant uye kubatanidzwa mukutonga kwesimba, ALA yakadzidzwa kune akatevedzana ekurapa mashandisiro, kusanganisira yeropa optimization.

 

Hukama pakati peAlpha Lipoic Acid uye Kumanikidzwa kweRopa

 

Zvidzidzo zvakati wandei zvakaongorora kana ALA ichikanganisa mazinga eropa. Nzira dzakarongwa dzinosanganisira kuderedza oxidative kusagadzikana, kuvandudza endothelial basa uye nitric oxide kugadzirwa, uye modulating nzira dzechiratidzo dzinokanganisa vascular tone uye fluid balance. Kuburikidza nemhedzisiro yakadai, ALA yekuwedzera inogona kusimudzira vasodilation uye kubuda kwemvura, nekudaro ichideredza BP.

 

Imwe tsvagiridzo inoratidzawo ALA inobatsira kudzoreredza endo native antioxidants senge vhitamini C, zvisina kunanga ichikudza mabhenefiti ayo evascular. Kuwedzera anti-kuzvimba mhedzisiro yeALA inogonawo kukanganisa BP. Nepo zvakawanikwa zvichiti zvakasanganiswa, ongororo dzinoverengeka dzinoratidza kudzikisira zvine mwero kweBP, kunyanya muvanhu vane hypertension. Nekudaro, mhedzisiro inoratidzika zvinoenderana nedosi, ichiratidza kudikanwa kwekuwedzera kutsvagisa pane yakakwana dosing nzira.

 

Iyo Alpha Lipoic Acid Yakaderera Ropa Kuwedzera?

 

Pakazere, tsvagiridzo pamusoro peiyo antihypertensive mhedzisiro yeALA yekuwedzera inoratidza imwe vimbiso asi inopa yakasanganiswa mhedzisiro:

- A 2011 meta-analysis yakashuma avhareji systolic uye diastolic kuderedzwa kweropa kwe4.39 uye 2.04 mmHg, zvichiteerana, ne alpha-lipoic acid powder. Zvisinei, zvikomborero zvaive zvakakura muzvidzidzo zvekushandisa 600mg zuva nezuva kwemavhiki e4-12.

- Sezvineiwo, 2015 ongororo yakarongeka yakawana humbowo husingaverengeki hweALA pamusoro peropa. Nekudaro, data rekubatanidza rakaratidza kudzikiswa zvine mwero mu diastolic blood pressure. Migumisiro yainyanya kuoneka muvanhu vakafuta.

- A 2016 randomized controlled trial mu obese hypertension varwere vakawana 300mg ALA zuva nezuva zvakanyanya kuderedza systolic uye diastolic blood pressure kana ichienzaniswa ne placebo mushure memavhiki masere.

- Zvimwe zvidzidzo zvinoratidza kusakosha kwakakosha kana glucose-kudzikisa mhedzisiro yeALA paBP yerudzi rwe2 chirwere cheshuga, zvisinei nekutarisa mumhando dzemhuka.

Pakazere, ALA yekuwedzera inoratidza mukana wekubatsira kudzora kweropa mune vamwe vanhu, asi mishonga yekurapa uye kuchengetedzwa kwenguva refu kunoda kumwe kutsvagisa. Mhedzisiro ingangoenderana nehuwandu hweoxidative kusagadzikana uye yekutanga BP mazinga.

 

Alpha Lipoic Acid Inoshanda Sei Mumuviri?

 

ALA inotorwa nyore kubva mukudya uye inoyambuka maseru membranes nyore kuita systemic mhedzisiro. Sezvo zvese zviri zviviri mvura uye mafuta-anonyungudika, ALA nemametabolites ayo anogona kunanga oxidative kusagadzikana mukati memuviri matishu uye zvinwiwa. Heano mamwe emaitiro ayo ekuita:

-Kudzoreredza antioxidants senge glutathione, mavhitaminzi C uye E.

- Kudzvinyirira nzira dzekuzvimba, adhesion mamorekuru, uye eicosanoid synthesis.

-Kuita AMP-activated protein kinase (AMPK), iyo inodzora kukwira kweglucose, kuyerera kweropa, uye mitochondrial basa.

-Kuwedzera kugadzirwa kwenitric oxide, kukonzeresa vasodilation, uye kuderedza BP.

- Chelating redox-inoshanda shanduko simbi inogona kukonzera oxidative kukuvara.

- Modulating chiratidzo mapuroteni anodzora huwandu hwemvura uye vascular kuramba.

Kuburikidza neaya antioxidant, anti-kuzvimba, uye kusaina mhedzisiro, ALA inogona kupa vasoprotective mabhenefiti ayo anobatsira kudzikira kweropa.

 

Zvinotarisirwa Pakutarisira Kufurirwa Kweropa

 

Avo vanofarira ALA yekuwedzera kweBP vanofanira kucherechedza:

- Mhedzisiro inogona kutsamira padanho rekutanga reBP, zvinokonzeresa hypertension, ALA dosages, uye nguva yekushandiswa.

- ALA inogona kudyidzana nemishonga yehypertension seACE inhibitors kana diuretics. Bvunza vanachiremba usati wabatanidza.

-Chengetedza kukwira kweropa nguva dzose, sezvo ALA yekuwedzera yega haigone kukwana kune akawanda ane mwero / akanyanya hypertension kesi.

- Wedzera magnesium, B mavhitaminzi, CoQ10 kudya pamwe nekuwedzera kudzivirira kwemoyo.

- Rega kushandisa kana uine zviratidzo zvakaita semusoro, kumhanya kwemoyo, dzungu, kurira, kana kusagadzikana kwemhasuru.

Kune hypertension, kuchinja kwehupenyu hwemazuva ose uye mishonga yemishonga inofanira kutora nzvimbo yekutanga zvichienderana nehutungamiri hwezvechiremba.ALA inogona kupa rubatsiro rwekubatsira kana yakanyatsobatanidzwa muurongwa hwekurapa kwese.

 

Ndeipi Mishonga Isingagone Kutorwa neAlpha-Lipoic Acid?

 

Kumwe kudyidzana kunogona kuitika pakati Alpha Lipoic Acid Poda nemimwe mishonga:

- Insulin nemishonga yechirwere cheshuga yemuromo - ALA inogona kuderedza mazinga eglucose uye kukanganisa dosage zvinodiwa.

- Thyroid hormones - ALA inogona kuwedzera thyroid hormone basa.

- Chemotherapy mishonga - ALA's antioxidant mhedzisiro inogona kukanganisa mamwe marapirwo echirwere.

-Anti-platelet uye anticoagulant zvinodhaka - ALA inogona kuwedzera njodzi yekubuda ropa.

Vanhu vanotora chero mishonga vanofanirwa kubvunza chiremba wavo wavanonyorera vasati vashandisa ALA supplements kuratidza kuchengetedzeka uye kwakakodzera. Kuongororwa kwekuchinja kwekushanda kwemishonga kunokurudzirwa zvakare.

 

Ngano uye Zvisizvo

 

- Nhema: ALA yekuwedzera inorapa hypertension vari voga.

- Chokwadi: ALA haina kuratidzwa inoshanda seyakamira-yega kurapa asi inogona kupa adjunctive rutsigiro pasi pekutariswa nachiremba.

- Nhema: Kutora ALA kunobvisa kudiwa kwemishonga yeropa.

- Chokwadi: Vanhu vazhinji vachiri kuda mishonga yeantihypertensive pamadosi akajairwa zvisinei ne ALA supplementation.

- Nhema: Iyo yakakwira iyo ALA dosi, iyo yakakura kuderedzwa kweropa.

- Chokwadi: Yakawandisa yakakwira ALA dosi inogona kukonzera mhedzisiro. Kuva nemwero kunorayirwa.

 

Zvazvinoita uye Mhedziso

 

Nepo izvo zvingangoita BP yeropa mabhenefiti ealpha lipoic acid inoda zvakanyanya kuomarara kudzidza, ayo antioxidant uye anti-kuzvimba zviitiko zvinopa biological plausibility yekudzivirira. ALA yekuwedzera inogona kupa kudzikisira kweropa zvine mwero kana ikashandiswa zvine hungwaru uye nekuchengetedza kwakakodzera. Nekudaro, hypertension yakaoma, yakawanda-yakawanda mamiriro inoda echinyakare humbowo-hwakavakirwa marapirwo semutsetse wekutanga wekurapa. ALA inofanirwa kungoonekwa senge inogona kutsigira adjunct zvichienderana nezvido zvemunhu uye tarisiro yekurapa. Tsvagiridzo inoenderera mberi ichabatsira kunatsiridza kutungamira kwekushandisa zvine hungwaru kweALA yekuwedzera yekudzora kweropa.

 

Iyo kambani Shaanxi Hongda Phytochemistry Co., Ltd. inoshandisa mitsetse mitanhatu yekugadzirwa kwepamusoro panguva imwe chete, ichibvumira kubuda kwezuva nezuva kwematani gumi uye inoyevedza yegore inobuda inosvika zviuru zvematani akati wandei. Nevashandi vakazvitsaurira vevashandi vangangosvika mazana matatu, kambani yakakamurwa kuita madhipatimendi akasiyana siyana kusanganisira kugadzira, Packaging, kutenga, kuchengetedza uye kutakura, kuongororwa kwehutano, kutengesa, kushanda, mari, nezvimwe. Hongda Phytochemistry inosimudzira yakaomesesa zviyero mukati memaitiro avo ekugadzira, vachiomerera kune ISO uye GMP zviyero. Chete mushure mekupfuura kuongororwa kwakaomarara izvo zvigadzirwa zvavo zvinozviita mukuchengetedza. Semutengesi ane mukurumbira we alpha lipoic acid yakawanda poda, Hongda Phytochemistry yakazvipira kupa vatengi zvigadzirwa zvemhando yepamusoro pamitengo yemakwikwi. Kune chero kubvunza kana rumwe ruzivo, ndapota usazeza kuvabata pa duke@hongdaherb.com, uko boka ravo rakagadzirira kukushandirai nomwoyo wose.

 

References:

 

1. Gomes, MB chii chimwe, Negrato, CA, 2014. Alpha-lipoic acid semushonga wepleiotropic uye unotarisirwa kushandiswa kwekugadzirisa chirwere cheshuga nezvimwe zvirwere zvinoramba zvichiitika. Diabetology uye metabolic disorder, 6 (1), pp.1-7.

2. de Oliveira, AM, Rondó, PH zvakare, Luzia, LA, 2015. Mhedzisiro ye lipoic acid uye α-tocopherol supplementation pane lipid profile uye insulin kuziva kwevarwere vane chirwere cheshuga 2 chirwere cheshuga mellitus: a randomized, akapetwa kaviri asingaoneki, kurapwa kwenhema kunodzorwa kwekutanga. Tsvakurudzo yechirwere cheshuga uye kliniki tsika, 108 (2), mapeji 253-260.

3. Zhang, Y., Han, P., Wu, N., He, B., Lu, Y., Li, S., Liu, Y., Zhao, S., Liu, L. zvakare, Li, Y., 2011. Kuwedzerwa kwelipid anomalies ne-α-lipoic acid kuburikidza ne-antioxidative uye kuderedza maitiro. Corpulence, 19(8), p.1647-1653.

4.de Oliveira, AM, Rondo, PH, Luzia, LA, D'Abronzo, FH chii chimwe, Illison, VK, 2011. Migumisiro ye lipoic acid uye α-tocopherol supplementation pane lipid profile uye insulin kuziva kwevarwere vane chirwere cheshuga 2 chirwere cheshuga mellitus: a randomized, maviri akapetwa kaviri, fake yekuona isingaoneki. Tsvakurudzo yechirwere cheshuga uye kliniki tsika, 92 (2), pp.253-260.